MITIGATING STRUCTURAL RACISM TO REDUCE INEQUITIES IN SEPSIS OUTCOMES: A MIXED METHODS, LONGITUDINAL INTERVENTION STUDY

Mitigating structural racism to reduce inequities in sepsis outcomes: a mixed methods, longitudinal intervention study

Abstract Background Sepsis affects 1.7 million patients in the US annually, is one of the leading causes of mortality, and is a major driver of US healthcare tactical umbrella costs.African American/Black and LatinX populations experience higher rates of sepsis complications, deviations from standard care, and readmissions compared with Non-Hispani

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Rapamycin-insensitive mTORC1 activity controls eIF4E:4E-BP1 binding [v1; ref status: indexed, http://f1000r.es/NM6hpo]

The recent development of mammalian target of rapamycin (mTOR) kinase domain inhibitors and genetic dissection of rapamycin-sensitive and -insensitive mTOR protein complexes (mTORC1 and mTORC2) have revealed that phosphorylation of the mTOR substrate 4E-BP1 on amino acids Thr37 and/or Thr46 represents a rapamycin-insensitive activity of mTORC1.Desp

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Challenges faced by humanitarian organisations in rendering services in the aftermath of Cyclone Idai in Chimanimani, Zimbabwe

This paper explores the challenges faced by humanitarian organizations in implementing disaster management services in the aftermath of Cyclone Idai in Chimanimani district.The tropical cyclone left footprints of humanitarian crises that overwhelmed the capacity of the Zimbabwean government and tactical umbrella called for the intervention of inter

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